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病毒组文章

01

Microbiol Spectr:慢性阻塞性肺病患者的肠道病毒组变化

近年来,病毒宏基因组学的进步揭示了肠道病毒组在人类健康和疾病中的重要作用,包括与宿主免疫系统的相互作用以及对代谢的调节。根据肠-肺轴的概念,肠道微生物群可以影响呼吸和肺部免疫,这暗示了肠道微生物组在调节包括COPD在内的呼吸和肺部疾病的炎症反应中的关键作用。

Liu Y, Huang Q, Zhuang Z, Yang H, Gou X, Xu T, Liu K, Wang J, Liu B, Gao P, Cao F, Yang B, Zhang C, Chen M, Fan G.2024.Gut virome alterations in patients with chronic obstructive pulmonary disease. Microbiol Spectr12:e04287-23.https://doi.org/10.1128/spectrum.04287-23

02

Animal Microbiome:腹泻型丹顶鹤的病毒组特征

山东省农业科学院的崔宁老师等在Animal Microbiome发表了一篇题为Virome characterization of diarrheic red-crowned crane(G. japonensis)的研究论文,该研究检测和表征了山东省东营生物圈保护区内圈养繁殖的丹顶鹤的病毒组,并探索了导致圈养丹顶鹤腹泻死亡的可能的病毒病因。

Cui, N., Yang, X., Sui, H. et al. Virome characterization of diarrheic red-crowned crane (G. japonensis). anim microbiome 6, 8 (2024). https://doi.org/10.1186/s42523-024-00299-3

03

Gut Microbes:肠道病毒组的改变与II型糖尿病和糖尿病肾病相关

该研究重点探索T2D患者肠道病毒组的变化及其与肠道细菌的关系,探讨病毒组的变化是否与DN有关,以增加对肠道微生物群在T2D及其并发症发病机制中作用的了解,也为代谢性疾病的诊断和治疗提供新的线索。

Fan G, Cao F, Kuang T, Yi H, Zhao C, Wang L, Peng J, Zhuang Z, Xu T, Luo Y, Xie Y, Li H, Zhang K, Zeng Y, Zhang X, Peng S, Qiu X, Zhou D, Liang H, Yang B, Kang J, Liu Y, Zhang Y. Alterations in the gut virome are associated with type 2 diabetes and diabetic nephropathy. Gut Microbes. 2023 Jan-Dec;15(1):2226925. doi: 10.1080/19490976.2023.2226925. PMID: 37349979; PMCID: PMC10291934.

04

FRONT IMMUNOL:病毒组与宏基因组分析揭示了妊娠期间人类胎儿肠道微生物群的不同分布

四川大学张曜耀与范振兴团队利用病毒组学技术,发现了胎儿肠道中存在丰富多样的微生物群,包括细菌、古菌和病毒及噬菌体,为早期胎儿免疫相关的研究提供了支持。

Liu X, He G, Lan Y, Guo W, Liu X, Li J, Liu A, He M, Liu X, Fan Z, Zhang Y. Virome and metagenomic analysis reveal the distinct distribution of microbiota in human fetal gut during gestation. Front Immunol. 2023 Jan 5;13:1079294.

噬菌体文章

He P, Cao F, Qu Q, Geng H, Yang X, Xu T, Wang R, Jia X, Lu M, Zeng P, Luan G. Host range expansion of Acinetobacter phage vB_Ab4_Hep4 driven by a spontaneous tail tubular mutation. Front Cell Infect Microbiol. 2024 Feb 16;14:1301089. doi: 10.3389/fcimb.20

Qu Q, Chen T, He P, Geng H, Zeng P, Luan G. Isolation and characterization of a novel lytic bacteriophage vB_Efm_LG62 infecting Enterococcus faecium. Virus Genes. 

其他文章

Zeng, X., Guo, Y., Xu, Q. et al. Origin and evolution of qingke barley in Tibet. Nat Commun 9, 5433 (2018).

Zeng, X., Xu, T., Ling, Z. et al. An improved high-quality genome assembly and annotation of Tibetan hulless barley. Sci Data 7, 139 (2020).

Liu W, Chen M, Bai L, Zhuang Z, Fan C, Jiang N, Zhao J, Ma S, Xiang X. Comprehensive transcriptomics and proteomics analyses of pollinated and parthenocarpic litchi (Litchi chinensis Sonn.) fruits during early development. Sci Rep. 2017.

Shi X, Wu J, Mensah RA, Tian N, Liu J, Liu F, Chen J, Che J, Guo Y, Wu B, Zhong G, Cheng C. Genome-Wide Identification and Characterization of UTR-Introns of Citrus sinensis. Int J Mol Sci. 2020.

Li, G., Yang, Q., Li, D., Zhang, T., Yang, L., Qin, J., Tang, B., Guo, X., Cao, Y., You, S., Li, Z., Luo, J., Wan, X., Liu, Y., Huang, F., Guo, L., Jiang, K. and Zheng, J. (2021), Genome-wide SNP discovery and QTL mapping for economic traits in a recombinant inbred line of Oryza sativa. Food Energy Secur.

Chen X, Tao Y, Ali A, Zhuang Z, Guo D, Guo Q, Riaz A, Zhang H, Xu P, Liao Y, Wang J, Sun C, Xiang Q, Wu X. Transcriptome and Proteome Profiling of Different Colored Rice Reveals Physiological Dynamics Involved in the Flavonoid Pathway. Int J Mol Sci. 2019 .

Zhoufeng Wang*; Kailing Tu*; Lin Xia*; Kai Luo*; Wenxin Luo*; Jie Tang; Keying Lu;Xinlei Hu; Yijing He; Wenliang Qiao; Yongzhao Zhou; Jun Zhang; Feng Cao; Shuiping Dai;Panwen Tian; Ye Wang; Lunxu Liu; Guowei Che; Qinghua Zhou; Dan Xie(#) and WeiminLi(#), The Open Chromatin Landscape of Non-small Cell Lung Carcinoma. Cancer Research.

Feng Cao*, Ailin Wei* , Xinlei Hu, Yijing He, Jun Zhang, Lin Xia, kailing Tu, Jue Yuan, Ziheng Guo, Hongying Liu, Dan Xie, Ang Li. Integrated Epigenetic Biomarkers in Circulating Cell-free DNA as a Robust Classifier for Pancreatic Cancer. Clinical Epigenetics.

Jiankun Y , Lichao Y , Baixue L , Yang Bin,et al. iTRAQ-Based Proteomics Identification of Serum Biomarkers of Two Chronic Hepatitis B Subtypes Diagnosed by Traditional Chinese Medicine[J]. BioMed Research Internationa.

Song Lingjie#, Yang Xianggui#, Huang Jinwei, Zhu Xiaokui, Han Guohui, Wan Yan, Xu Ying, Luan Guangxin*, Jia Xu*.(2021) Phage Selective Pressure Reduces Virulence of Hypervirulent Klebsiella pneumoniae Through Mutation of the wzc Gene .Frontiers in Microbiology.